TB-500 10mg Kit

Thymosin Beta-4 Fragment | 5 Vials × 2mg

Product Name: TB-500 (Thymosin Beta-4 Synthetic Fragment)
CAS Number: 77591-33-4
Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈
Molecular Weight: 4963.44 g/mol
Purity: ≥99% (verified by HPLC & Mass Spectrometry)
Appearance: White lyophilized powder
Packaging: Sold as a kit of 5 vials × 2mg (10mg total)

Product Overview

TB-500 is a synthetic peptide derived from the naturally occurring protein Thymosin Beta-4 (TΒ4), which is present in nearly all human and animal cells. This research peptide replicates the active region of TΒ4 responsible for its regenerative and cytoprotective properties. TB-500 is widely studied for its role in cellular migration, angiogenesis, and tissue repair mechanisms.

Each kit contains 5 individual 2mg vials, allowing for convenient dosing flexibility and extended shelf life, as unused vials remain lyophilized and stable until reconstitution.

Mechanism of Action

TB-500 functions by upregulating actin, a protein essential for cell structure and movement. Through actin binding, it promotes:

• Cellular migration to sites of injury
• New blood vessel formation (angiogenesis)
• Reduction of inflammatory markers
• Differentiation of stem cells into functional tissue
• Modulation of extracellular matrix remodeling

Research Applications

• Studies on soft tissue repair and wound healing
• Investigations into tendon, ligament, and muscle recovery models
• Cardiac tissue regeneration research
• Corneal and dermal healing studies
• Anti-inflammatory pathway research
• Hair follicle and stem cell migration studies

Reconstitution & Storage

Reconstitution: Use bacteriostatic water or sterile saline. Typical dilution is 1–2 mL per 2mg vial.
Storage (Lyophilized): Store at -20°C for long-term stability. Stable at room temperature for short transit periods.
Storage (Reconstituted): Refrigerate at 2–8°C and use within 14–30 days.
Shelf Life: 24 months from manufacture date when stored properly.

Kit Contents

• 5 × 2mg lyophilized TB-500 vials (sealed, sterile)
• Tamper-evident flip-off caps
• Batch-specific lot number on each vial
• Certificate of Analysis (COA) available upon request

Quality Assurance

Every batch is independently third-party tested for purity, identity, and sterility. HPLC and Mass Spectrometry reports are available with your order. Manufactured in an ISO-certified facility under strict GMP-aligned standards to ensure batch-to-batch consistency.

Sequence

Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH